Functional Annotation of Variants
Online Resource
An open-access portal for whole genome sequencing variant annotation. Accelerating variant interpretation and discovery.
8.9B
TOTAL VARIANTS
8.8B
POSSIBLE SNVS
80M
OBSERVED INDELS
Upload a variant file
CSV, TSV, VCF, or Parquet. Get back an annotated variant list you can query, browse, and download.
Documentation
What columns we accept, what identifier styles we recognize, and what makes a file parse cleanly.
Upload a file
CSV, TSV, VCF, or Parquet. We handle parsing and column mapping.
Up to 50MBRun it locally
Skip the upload. The CLI for new work, the R Annotator for existing STAARpipeline setups.
Recommended
FAVOR CLI
Annotate, add tissue context, and run rare-variant tests on your own hardware. Replaces the R Annotator for new work.
FAVOR Annotator
R program plus the FAVOR database (Essential and Full) on Harvard Dataverse. For existing STAARpipeline setups — for new work, use the CLI.